Registration Dossier
Registration Dossier
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EC number: 203-532-3 | CAS number: 107-92-6
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only secondary literature
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 1 981
- Report date:
- 1981
- Reference Type:
- review article or handbook
- Title:
- Report to RIFM, 01 July 1977
- Author:
- Epstein Wl Report to RIFM, 01 July 1977 (cited from Opdyke 1979)
- Year:
- 1 977
- Bibliographic source:
- Research Institute for Fragrance Materials, cited in Opdyke (1981)
- Report date:
- 1977
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 975
- Report date:
- 1975
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Maximization test according to Kligman and Epstein (1975)
- GLP compliance:
- no
- Type of study:
- other: maximization test
Test material
- Reference substance name:
- Butyric acid
- EC Number:
- 203-532-3
- EC Name:
- Butyric acid
- Cas Number:
- 107-92-6
- Molecular formula:
- C4H8O2
- IUPAC Name:
- butyric acid
- Details on test material:
- - Name of test material (as cited in study report): n-butyric acid, n-butanoic acid (RIFM no. 77-60)
- no further information reported
Constituent 1
In vivo test system
Test animals
- Species:
- human
Results and discussion
Any other information on results incl. tables
No sensitization reaction was produced by the test substance (1% in petrolatum) in the test system used.
Applicant's summary and conclusion
- Interpretation of results:
- not sensitising
- Remarks:
- Migrated information
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