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EC number: 203-453-4 | CAS number: 107-02-8
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Acrolein does not contain any hydrolysable groups, but it does react with water in a reversible hydration reaction to 3-hydroxypropanal (HPA).
Key value for chemical safety assessment
Additional information
1. European Union Risk Assessment Report of Acrolein (EU, 2001)
Acrolein does not contain any hydrolysable groups, but it does react with water in a reversible hydration reaction to 3-hydroxypropanal (HPA). The half-life for this reaction was found to be 15 hours in sewage water, 45 hours in drinking water and up to 11 days in de-ionised water. Besides this reaction step HPA reacts in a secondary reaction with acrolein to 3,3’-oxydipropionaldehyde, which further reacts to other secondary products. In field studies (irrigation canals) half-life values for the elimination of acrolein between 3 and 7 hours were calculated. Apparently, processes other than hydration, e.g. volatilisation, also contribute to acrolein dissipation in the aquatic environment.
2. Agreement with further international Reports and Studies published after finalisation of the EU Risk Assessment Report 2001
US ATSDR (2007): Kissel et al. measured acrolein removal in buffered laboratory water and natural river water using both chemical analysis methods and bioassays. Complete hydrolysis (which according to the authors includes hydration to 3-hydroxypropanal) occurred within 150, 120 -180, and 5-40 hours in buffered solutions at 22 °C and pH 5, 7, and 9, respectively.
3. Substantial disagreements in comparison to further international Reports to European Union Risk Assessment Report 2001
None
4. Additional aspects in further international Reports
None
5. Additional information in newer Studies, not included in the European Union Risk Assessment Report 2001 or further cited international reports
None
6. Conclusions
Acrolein does not contain any hydrolysable groups, but it does react with water in a reversible hydration reaction to 3-hydroxypropanal (HPA). The half-life for this reaction was found to be 15 hours in sewage water, 45 hours in drinking water and up to 11 days in de-ionised water. Besides this reaction step HPA reacts in a secondary reaction with acrolein to 3,3’-oxydipropionaldehyde, which further reacts to other secondary products. In field studies (irrigation canals) half-life values for the elimination of acrolein between 3 and 7 hours were calculated. Apparently, processes other than hydration, e.g. volatilisation, also contribute to acrolein dissipation in the aquatic environment.
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