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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Genetic toxicity: in vitro

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Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Remarks:
Type of genotoxicity: gene mutation
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
No information
Author:
Anonymous
Year:
2011
Bibliographic source:
NICNAS (Australia)

Materials and methods

Test guideline
Guideline:
other: OECD
GLP compliance:
not specified
Type of assay:
bacterial reverse mutation assay

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
435-740-7
EC Name:
-
Cas Number:
94317-64-3
Molecular formula:
C4H14N3PS
IUPAC Name:
Phosphorothioic triamide, N-butyl-

Method

Species / strain
Species / strain / cell type:
S. typhimurium, other: TA98, TA100, TA1535, TA1537
Metabolic activation:
with and without
Metabolic activation system:
no data
Test concentrations with justification for top dose:
between 333 and 500 microgram per plte, resp. 0.1 to 5.0 milligram/l

Results and discussion

Test results
Species / strain:
S. typhimurium, other: TA98, TA100, TA1535, TA1537
Metabolic activation:
with and without
Genotoxicity:
negative
Cytotoxicity / choice of top concentrations:
not determined
Additional information on results:
All results were negative

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information):
negative