Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 271-832-1 | CAS number: 68609-68-7 The complex combination of products produced by the distillation of products from a 2-ethyl-1-hexanol manufacturing process. It consists predominantly of organic compounds such as alcohols, aldehydes, esters, carboxylic acids and acetals having carbon numbers predominantly in the range of C4 through C16 and boiling in the range of 150°C to 308°C (302°F to 586°F).
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. Residues, a complex mixture of non-ionic organic substances is a clear light brown liquid UVCB item with a solubility of 0.79 g/L in demineralised water at 20°C, a log Pow of 1.6, a vapour pressure of 19 Pa at 20°C and boiling point(s) ranging from 201 to 365°C. The substance consists of at least 25 components, four of them could be identified. The identified constituents are in a moleclar weight range of 72 -260 Da. Based on the starting materials and the manufacutring process constituents with a molecular weight above 500 Da are not expected The main toxicokinetic properties of 1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. Residues are assessed on the basis of its physico-chemical properties and with special regard to the results of the standard toxicity tests performed with this test item.
The log Pow, water solubility and the molecular weight distribution of 1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. Residues indicate a moderate to high absorption via all routes after exposure.
Only four out of 25 detected components could be structurally characterised. Therefore it is not possible to predict the metabolic pathway for the majority of the components. Within the data set, there is no indication for toxic metabolite formation associated with exposure to 1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. Residues. This finding is supported by the lack of both, specific target organ toxicity following repeated dose exposures and the lack of differences in genotoxicity and cytotoxicity when comparing 1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. Residues exposed cell cultures with and without a metabolic activation system.
Based on the above-mentioned properties, water soluble 1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. Residues and its potential polar metabolites are considered to be rapidly and quantitatively excreted in the urine. The log Pow indicates no potential for accumulation in the tissues.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
