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EC number: 204-279-1 | CAS number: 118-82-1
Mean values for endpoints
Dietary level (%)
Number females pregnant (10 bred)
Numbers in litter
Live, Day 4
When pregnant rats were given diets containing test article at concentrations of 0.125 to 1.25% of the dry weight of the food, there were no effects on length of gestation, size of pups, or total number of young per litter. There was not an increase compared to control in numbers of stillborn pups in the litters. In comparison, feeding N,N’-diphenyl-p-phenylenediamine (DPPD) was associated with increase in incidence of stillborns, but not an effect on numbers of young in the litters or offspring weights. DPPD in the basal diet with adequate vitamin E caused prolonged gestation in 3 of 10 rats which, when lengthened to 25 days, resulted in death before parturition.
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