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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Sensitisation data (human)

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Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Basic data given.

Data source

Reference
Reference Type:
publication
Title:
Occupational skin diseases among the nurses in the region of Lodz.
Author:
Kiec-Swierczynska M. and Krecisz, B.
Year:
2000
Bibliographic source:
International Journal of Occupational Medicine and Environmental Health 13(3): 179-184

Materials and methods

Type of sensitisation studied:
skin
Study type:
study with volunteers
Principles of method if other than guideline:
223 nurses from the Lodz region, referred to the Nofer Institute of Occupational Medicine in 1995-99 because of suspected occupational dermatoses. The diagnosis of contact allergy was based on the positive results of patch tests, and immediate allergy to common allergens and latex on the results of prick tests, as well as on the determinations of specific IgE antibodies.
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Cobalt dichloride
EC Number:
231-589-4
EC Name:
Cobalt dichloride
Cas Number:
7646-79-9
IUPAC Name:
cobalt(2+) dichloride
Constituent 2
Reference substance name:
cobalt(II)chloride
IUPAC Name:
cobalt(II)chloride
Details on test material:
- Name of test material (as cited in study report): Cobalt chloride
- Analytical purity: 1.0%

Method

Type of population:
occupational
Controls:
no data
Route of administration:
dermal

Results and discussion

Results of examinations:
Contact allergy to cobalt chloride was diagnosed in 22 of 223 nurses (9.9%).

Applicant's summary and conclusion