Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

 Short-term toxicity to fish:

In freshwater as well as saltwater, with high probability not harmful to fish.

Freshwater: LC50 (96 h): 180 mg/L (Oncorhynchus mykiss, static conditions, analytically verified concentrations)

Saltwater: LC50 (96 h): 179 mg/L (Vala muli engeli, static, nominal, no analytical verification)

 

Long-term toxicity to fish:

No experimental data available.

 

Short-term toxicity to aquatic invertebrates:

Morpholine is acutely harmful to aquatic invertebrates.

EC50 (48 h): 45 mg/L (Daphnia magna, OECD 202, static)

 

Long-term toxicity to aquatic invertebrates:

EC10 (21 d): 8.134 mg/L (Daphnia magna, OECD 211, semi-static)

 

Growth inihibition to aquatic algae:

Morpholine is acutely toxic to aquatic algae (based on marine data).

Freshwater data:

ErC50 (96 h): 28 mg/L (Pseudokirchneriella subcapitata, EPA guideline, effect on growth, static, analytically verified concentrations)

NOErC (96 h): 10 mg/L (Pseudokirchneriella subcapitata, EPA guideline, effect on growth, static, analytically verified concentrations)

 

Saltwater data:

ErC50 (72 h): 9 mg/L (Skeletonema costatum, ISO 10253, effect on growth, static, nominal, no analytical verification)

 

Toxicity to microorganisms:

The inhibition of the degradation activity of activated sludge is not anticipated when introduced to biological treatment plants in appropriate low concentrations.

EC20 (30 min): > 1000 mg/L (OECD 209; one test with domestic activated sludge and two tests with industrial activated sludge)

EC3 (16 h): 310 mg/L (Pseudomonas putida)