Registration Dossier

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Short-term toxicity to fish:

With high probability not harmful to fish.

LC50 (96 h): > 100 mg/L (Oryzias latipes, semi-static conditions, analytically verified concentrations)


Long-term toxicity to fish:

No experimental data available.

NOEC (ACR method): > 1 mg/L


Short-term toxicity to aquatic invertebrates:

Morpholine is acutely harmful to aquatic invertebrates.

EC50 (48 h): 45 mg/L (Daphnia magna, OECD 202, static)


Long-term toxicity to aquatic invertebrates:

EC10 (21 d): 8.134 mg/L (Daphnia magna, OECD 211, semi-static)


Growth inihibition to aquatic algae:

Morpholine is acutely toxic to aquatic algae.

ErC50 (72 h): 65 mg/L (Pseudokirchneriella subcapitata, OECD 201, static, analytically verified concentrations)

ErC10 (72 h): 31 mg/L (Pseudokirchneriella subcapitata, OECD 201, static, analytically verified concentrations)


Toxicity to microorganisms:

The inhibition of the degradation activity of activated sludge is not anticipated when introduced to biological treatment plants in appropriate low concentrations.

EC20 (30 min): > 1000 mg/L (OECD 209; one test with domestic activated sludge and two tests with industrial activated sludge)

EC3 (16 h): 310 mg/L (Pseudomonas putida, growth inhibition test)

Additional information

Categories Display