Registration Dossier
Registration Dossier
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EC number: 271-231-4 | CAS number: 68526-83-0
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
Both an aqueous exposure bioconcentration test and a dietary exposure bioaccumulation test with Alcohols, C9 -11 -iso-, C10-rich (Isodecanol) were conducted with the rainbow trout, Oncorhynchus mykiss. In the aqueous exposure, the trout reached steady-state within a 16 -day exposure period. The calculated mean lipid normalized steady state BCF was 21.4 L/kg wet fish weight. The calculated dietary, lipid-corrected BMF values were 0.006 to 0.016 (at 500 and 2500 ppm treatment levels), with growth corrected whole body half-lives ranging from 0.55 to 0.21 days. These data are used as read-across for Alcohols, C7-9-iso, C8-rich.
Key value for chemical safety assessment
- BCF (aquatic species):
- 21.4 L/kg ww
Additional information
Both an aqueous exposure bioconcentration test and a dietary exposure bioaccumulation test with Alcohols, C9 -11 -iso-, C10-rich (Isodecanol) were conducted with the rainbow trout, Oncorhynchus mykiss. In the aqueous exposure, the trout reached steady-state within a 16 -day exposure period. The calculated mean lipid normalized steady state BCF was 21.4 L/kg wet fish weight. The calculated dietary, lipid-corrected BMF values were 0.006 to 0.016 (at 500 and 2500 ppm treatment levels), with growth corrected whole body half-lives ranging from 0.55 to 0.21 days.
The registered substance (Isooctanol) and the tested substance (Isodecanol) are part of a closely related group of products with structural similarity, made by the same manufacturing process. (Further detail is provided in the assessment report for read-across.) Their structural and physicochemical properties follow an expected trend with C-chain length. The tested substance is more hydrophobic and has a higher log Kow than the target substance. As BCF is positively correlated with hydrophobicity, these values can be used as a worst-case estimate for Alcohols, C7-9-iso, C8-rich. Both the aqueous and dietary bioaccumulation studies indicate that this substance exhibits a low potential to bioaccumulate.
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