Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-629-0 | CAS number: 108-91-8
Specific investigations: other studies
Administrative data
- Endpoint:
- biochemical or cellular interactions
- Type of information:
- experimental study
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 968
- Report date:
- 1968
Materials and methods
- Principles of method if other than guideline:
- RM-Freetext: Groups of 6 rats (not fasted) each received 0, 1, 3 or 10 mg/kg CHA per os. 1, 2, 4, and 6 hours after application blood was collected from the retro-orbital venous plexus and blood glucose determined. The same procedure was applied to fasted rats. Blood glucose was not different from control values for both fasted and not-fasted rats.
- GLP compliance:
- no
- Type of method:
- in vivo
- Endpoint addressed:
- not applicable
Test material
- Reference substance name:
- Cyclohexylamine
- EC Number:
- 203-629-0
- EC Name:
- Cyclohexylamine
- Cas Number:
- 108-91-8
- Molecular formula:
- C6H13N
- IUPAC Name:
- cyclohexanamine
- Details on test material:
- no further data
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: feed
- Vehicle:
- other: mixed in diet
- Analytical verification of doses or concentrations:
- not specified
- Duration of treatment / exposure:
- once
- Frequency of treatment:
- up to 6 hours post application
Doses / concentrations
- Remarks:
- Doses / Concentrations:
0, 1, 3, 10 mg/kg bw
Basis:
- No. of animals per sex per dose:
- 6 fasted and 6 not-fatsted
- Control animals:
- yes
Results and discussion
- Details on results:
- Blood glucose was not different from control values for both fasted and not-fasted rats.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
