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Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Water solubility:
ca. 0.429 g/L
Temp.:
20 °C
pH:
ca. 6.5
Remarks on result:
other: The pH of the aqueous sample was determined after 72 hours stirring.
Details on results:
The results for the samples taken at 24, 48 and 72 hours are given in Table 1 below.
The maximum difference (MD) of the concentrations determined in the 24, 48 and 72 hour test samples was 15 %. According to the guidelines, the water solubility of the test substance is given as the mean value of the analysed concentrations.
In the pre-treated sample from the bank water mixture a small response was observed, the maximum contribution was 0.06 %, thus neglegible.

Table 1. Main study - water solubility of PURASOLV®EHL (2-ethylhexyl-S-lactate).

Stirring time

(hours)

Analysed concentration (g/l)

Mean (g/l)

MD (%)

pH

24

0.428

0.429

1.8

6.8

48

0.434

 

 

6.7

72

0.426

 

 

6.5

 

Conclusions:
2-Ethylhexyl-S-lactate is moderately soluble in water.
Executive summary:

The flask method was chosen for the determination of the water solubility of PURASOLV®EHL (2 -ethylhexyl-S-lactate). The water solubility of the test substance at 20 °C was 0.429 g/L. The pH of the aqueous sample after 72 hours stirring was 6.5.

Description of key information

The water solubility of 2 -ethylhexyl-S-lactate, determined using the flask method, is 0.429 g/L at 20 °C. The pH of the aqueous sample after 72 hours stirring was 6.5.

Key value for chemical safety assessment

Water solubility:
0.429 g/L
at the temperature of:
20 °C

Additional information