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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study with limited documentation and with no data on GLP compliance. In the OECD SIDS on 2-Naphthol (2002) a similar reliability was assigned.

Data source

Reference
Reference Type:
publication
Title:
Trans Am Fish Soc 113
Author:
Milllemann RE et al
Year:
1984
Bibliographic source:
Millemann RE et al; Trans Am Fish Soc 113 (1): 74-85 (1984)

Materials and methods

Test guideline
Guideline:
other: Acute Toxicity to Fish
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2-naphthol
EC Number:
205-182-7
EC Name:
2-naphthol
Cas Number:
135-19-3
Molecular formula:
C10H8O
IUPAC Name:
2-naphthol

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Details on test solutions:
Test solution was prepared with well water (pH: 7.8; alkalinity and hardness 120 and 140 mg/l as CaCO3)

Test organisms

Test organisms (species):
Pimephales promelas

Study design

Test type:
static
Water media type:
freshwater
Total exposure duration:
96 h

Test conditions

Hardness:
alkalinity and hardness 120 and 140 mg/l as CaCO3
Test temperature:
20 +/- 0.5 degree C
pH:
7.8
Dissolved oxygen:
DO changes from a mean of 8.5 mg/l at time 0 to 4.3 mg/l resp. 6.5 mg/l after 48 h.
Salinity:
no data
Nominal and measured concentrations:
no data
Details on test conditions:
7.6-liter aquaria covered with aluminium foil were used as test vessels; each aquaria contained 6 l of test solution and 5 fish. 2 aquaria were used for each of the 3 to 4 test concentrations.

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
3.46 mg/L
Remarks on result:
other: Juvenile; 95 % Conf. Lim. 2.43 - 3.90 mg/l

Applicant's summary and conclusion

Conclusions:
A test on acute toxicity to fish for 96h shows a value of LC50 of 3.46 mg/L.