Registration Dossier
Registration Dossier
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EC number: 203-920-2 | CAS number: 111-91-1
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Bis(2-chloroethoxy)methane is not mutagenic based on the results of an Ames test and two in vivo micronucleus tests.
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Short description of key information:
Four Ames tests are available with bis(2-chloroethoxy)methane two of these studies meets the current guideline and are performed under GLP. These two studies give a negative result. The NTP has performed 2 in vivo micronucleus assays in bone marrow and periferal blood of mice. Both studies were negative.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
An Ames test and two in vivo micronucleus tests show that Bis(2-chloroethoxy)methane is not mutagenic.
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