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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

Bis(2-chloroethoxy)methane is not mutagenic based on the results of an Ames test and two in vivo micronucleus tests.


Short description of key information:

Four Ames tests are available with bis(2-chloroethoxy)methane two of these studies meets the current guideline and are performed under GLP. These two studies give a negative result. The NTP has performed 2 in vivo micronucleus assays in bone marrow and periferal blood of mice. Both studies were negative.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

An Ames test and two in vivo micronucleus tests show that Bis(2-chloroethoxy)methane is not mutagenic.