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EC number: 500-090-6 | CAS number: 36425-16-8
In a developmental study the substance was administered to Sprage-Dawley rats 24/sex/dose by gavage at dose levels of 0, 100, 300 or 1000 mg/kg bw/day. Clinical symptoms, body weight and food consumption were recorded, and the uterus of females (number of corpora lutea, number, position and type of intrauterine implantation, placental weight, gravid uterus weight) and fetuses (total number, sex, weight and external, visceral-one-half and skeletal-one-half defects) were examined.There were no compound related effects in the dams or the offspring for the parameters monitored. The NOEL is 1000 mg/kg bw/day (the highest dose employed).
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