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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2009-04-27 to 2009-07-21
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP guideline study
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Remarks:
signed 2007-03-21
Type of method:
flask method
Water solubility:
>= 0.4 - <= 1.2 µg/L
Temp.:
20 °C
pH:
5.5
Details on results:
Under the conditions of this test (under exclusion of CO2 and O2 by argon atmosphere; flask method; loading 2g/L), the water solubility of diantimony tris(ethylene glycolate) at 20°C +/- 1°C could be determined between 0.4µ/L and 1.2µg/L (determined as dissolved Sb, separated by centrifugation from undissolved test item). Equlibrium was reached after 9 days stirring. The resulting pH value was approx. 5.5. Solubility is based on ICP-MS measurement of dissolved antimony. The test item was pulverized before the performance of the test.

ICP-MS analyses of the samples confirmed the low antimony concentration below 15µg/L. After 216, 240 and 264h the Sb concentrations were between 0.2 and 0.7µg/L. As a worst case scenario (larger surface) the date from the test with the pulverized test item diantimony tris(ethylene glycolate) were used. The mean values from the last three samplings (216 -264h) were constant with a difference below 15% between samplings (values of both test vessels were considered separately). Thus the mean value from each of these three samples was calculated as followes:

Test vessel I : 0.71 +/- 0.07 µg/L as Sb corresponds to 1.23 +/- 0.13µg/L as diantimony tris(ethylene glycolate); calculated for a theoretical Sb content of 57.5% (= factor 1.74)

Test vessel II : 0.22 +/- 0.01 µg/L as Sb corresponds to 0.38 +/- 0.02µg/L as diantimony tris(ethylene glycolate); calculated for a theoretical Sb content of 57.5% (= factor 1.74)

Conclusions:
Interpretation of results (migrated information): insoluble (< 0.1 mg/L)
The water solubility of diantimony tris(ethylene glycolate) at 20°C +/- 1°C could be determined between 0.4µ/L and 1.2µg/L . Equlibrium was reached after 9 days stirring. The resulting pH value was approx. 5.5

Description of key information

The water solubility of diantimony tris(ethylene glycolate) at 20°C +/- 1°C could be determined between 0.4µ/L and 1.2µg/L . Equilibrium was reached after 9 days stirring.

Key value for chemical safety assessment

Water solubility:
0.4 µg/L
at the temperature of:
20 °C

Additional information

Bio-accessibility data has also been generated, relevant to form read-across groups for systemic toxicological endpoints, as described in the relevant scientific opinions attached in Section 13.

 

(In CSR: Gastric bio-accessibility data has also been generated, relevant to form read-across groups for systemic toxicological endpoints, as described in the relevant scientific opinions included in the IUCLID file of the Registration Dossier)