Hexan-1-ol

Vapour pressure

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2009-09-10

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Test procedure in accordance with national standard methods (ASTM) without GLP. Measured by 100 °F (ca. 38 °C) instead of 20 °C.

Qualifier:

according to guideline

Guideline:

other: ASTM D 2879

Deviations:

yes

Remarks:

measured by 100 °F (ca. 38 °C) instead 20 °C.

GLP compliance:

no

Type of method:

isoteniscope

Temp.:

ca. 38 °C

Vapour pressure:

3.64 mBar

Measurement

Vapor Pressure at 100°F (Calculated): 2.733 mm Hg

Executive summary:

Hexan-1-ol was determined according ASTM D 2879. The vapour pressure was determined to be 3.64 mBar at 100°F (ca. 38 °C).

Reference 2

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Value obtained from a recognised source of physico-chemical data. This reference is considered as definitive for vapour pressure values.

Principles of method if other than guideline:

No details are available on the guideline used to determine this result.

GLP compliance:

not specified

Temp.:

25 °C

Vapour pressure:

124 Pa

Conclusions:

A vapour pressure value of 124 Pa at 25°C was reported in a collection of reliable data which has been subject to peer-review . The result is considered to be reliable.

Reference 3

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: see 'Remark'

Remarks:

The value is the extrapolated value at ambient temperature based on peer-reviewed raw vapour pressure data across a broad range of temperatures. The reference source is a well-known and reliable source of critically-reviewed vapour pressure data, which cites the original source of the data.

Principles of method if other than guideline:

No details are available on the guideline used to determine this result.

GLP compliance:

no

Temp.:

25 °C

Vapour pressure:

79.6 Pa

Transition / decomposition:

no

The value at 25ºC is determined using the Antoine Equation by applying three standard coefficients for use in that equation, derived

by Boublik et al. from reliable raw data.

Conclusions:

A vapour pressure value of 79.6 Pa at 25ºC is reported in a collection of reliable data which has been subject to peer-review and in which the original data sources are traceable. The result is considered to be reliable.

Reference 4

Endpoint:

vapour pressure

Type of information:

(Q)SAR

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification

Justification for type of information:

Please refer to attached justification documents

Principles of method if other than guideline:

Method: other (calculated): from composition

GLP compliance:

no

Temp.:

25 °C

Vapour pressure:

1.21 hPa

Conclusions:

A predicted vapour pressure of 121 Pa at 25°C was obtained for the substance.

Executive summary:

The vapour pressure of the substance has been predicted using a reliable method

Reference 5

Endpoint:

vapour pressure

Type of information:

calculation (if not (Q)SAR)

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Principles of method if other than guideline:

Method: other (calculated)

Temp.:

20 °C

Vapour pressure:

1.3 hPa

Description of key information

The vapour pressure of a commercial hexan-1-ol product is 3.64 mBar (364 Pa) at ca. 38°C. A consistent and reliable measurement of 124 Pa at 25°C using a highly pure sample is available (Daubert and Danner, 1989).

Key value for chemical safety assessment

Vapour pressure:

364 Pa

at the temperature of:

38 °C

Additional information

The vapour pressure of 364 Pa at ca. 38°C was determined for hexan-1-ol with the use of an isoteniscope method in accordance with ASTM D 2879. The result is considered to be reliable.

A consistent and reliable measurement of 124 Pa at 25°C using a highly pure sample is available (Daubert and Danner, 1989).

It is supported by a value of 79.6 Pa at 25°C for a pure product, taken from a reliable reference source Boublik et al, 1984).

The quantified value, determined with a pure substance at ambient temperature from Daubert and Danner is used in environmental modelling.

Discussion of trends in the Category of C6-24 linear and essentially-linear aliphatic alcohols:

As chain length increases, vapour pressure decreases. This is because molecular weight is higher and intermolecular forces in the substance are all higher.