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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Repeated dose toxicity: inhalation

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Administrative data

Endpoint:
sub-chronic toxicity: inhalation
Type of information:
not specified
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Performance description is not in compliance with an actual guideline, result description is incomplete as e.g. individual animal results are not shown

Data source

Reference
Reference Type:
publication
Title:
On the toxicity of cyclohexylamine and dicyclohexylamine.
Author:
Lomonova GV
Year:
1963
Bibliographic source:
Gig. Tr. Prof. Zabol 7, 51-56.

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
no data
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Dicyclohexylamine
EC Number:
202-980-7
EC Name:
Dicyclohexylamine
Cas Number:
101-83-7
Molecular formula:
C12H23N
IUPAC Name:
N-cyclohexylcyclohexanamine

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
not specified
Vehicle:
not specified
Remarks on MMAD:
MMAD / GSD: No data
Analytical verification of doses or concentrations:
not specified
Duration of treatment / exposure:
30d
Frequency of treatment:
daily
No. of animals per sex per dose:
No data

Results and discussion

Any other information on results incl. tables

The exposure period was tolerated without visible clinical symptoms.
Post exposure, treated mice were able to swim as long as untreated control mice .

Applicant's summary and conclusion