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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
other information
Study period:
1977
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Non-guideline study, insufficient documentation, only report of results without documentation of details
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
1977

Materials and methods

Principles of method if other than guideline:
Acute dermal toxicity
GLP compliance:
not specified
Test type:
standard acute method
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-chlorobenzaldehyde
EC Number:
201-956-3
EC Name:
2-chlorobenzaldehyde
Cas Number:
89-98-5
Molecular formula:
C7H5ClO
IUPAC Name:
2-chlorobenzaldehyde
Details on test material:
- Name of test material (as cited in study report): o-chlorobenzaldehyde (E-757)

Test animals

Species:
guinea pig
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
other: impervious cuff
Vehicle:
not specified
Duration of exposure:
no data
Doses:
5.0 to 20.0 g/kg
No. of animals per sex per dose:
3 animals at all

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
approximate LD50
Effect level:
20 000 mg/kg bw

Applicant's summary and conclusion

Executive summary:

In a study with guinea pigs which were dermally exposed to 5.0 to 20.0 g 2-chlorobenzaldehyde/kg bw no deaths were recorded.

Due to insufficient reporting the study was judged not to be reliable (RL3).