Registration Dossier

Classification & Labelling & PBT assessment

DSD-DPD

General information

Name:
dimethyl sulphate
Status:
67/548/EEC annex 1
Index number:
016-023-00-4
ATP inserted:
19
ATP last update:
29
Remarks:
Specific limits: yes
note E

Classification

Explosiveness

Reason for no classification:
conclusive but not sufficient for classification

Oxidising properties

Reason for no classification:
conclusive but not sufficient for classification

Flammability

Reason for no classification:
conclusive but not sufficient for classification

Thermal stability

Reason for no classification:
conclusive but not sufficient for classification

Acute toxicity

Classification:
T; R25 Toxic if swallowed.
T+; R26 Very toxic by inhalation.

Acute toxicity - irreversible damage after single exposure

Classification:
T; R39/25 Toxic: danger of very serious irreversible effects if swallowed.

Repeated dose toxicity

Reason for no classification:
conclusive but not sufficient for classification

Irritation / corrosion

Classification:
C; R34 Causes burns.

Sensitisation

Classification:
R43 May cause sensitisation by skin contact.

Carcinogenicity

Classification:
Carc. Cat. 2; R45 May cause cancer.

Mutagenicity - genetic toxicity

Classification:
Muta. Cat. 3; R68 Possible risk of irreversible effects.

Toxicity to reproduction - fertility

Reason for no classification:
data lacking

Toxicity to reproduction - development

Reason for no classification:
conclusive but not sufficient for classification

Toxicity to reproduction - breastfed babies

Reason for no classification:
data lacking

Environment

Reason for no classification:
conclusive but not sufficient for classification

Labelling

Indication of danger

T+ - very toxic

Risk phrases

R25 - Toxic if swallowed
R26 - Very toxic by inhalation
R34 - Causes burns
R43 - May cause sensitisation by skin contact
R45 - May cause cancer
R68 - Possible risk of irreversible effects

Safety phrases

S53 - avoid exposure - obtain special instructions before use
S45 - in case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)

Specific concentration limits

1. Concentration range (%):
>= 25
Classification:
T; R25 Toxic if swallowed.
T+; R26 Very toxic by inhalation.
C; R34 Causes burns.
R43 May cause sensitisation by skin contact.
Carc. Cat. 2; R45 May cause cancer.
Muta. Cat. 3; R68 Possible risk of irreversible effects.
2. Concentration range (%):
>= 10 - < 25
Classification:
Xn; R22 Harmful if swallowed.
T+; R26 Very toxic by inhalation.
C; R34 Causes burns.
R43 May cause sensitisation by skin contact.
Carc. Cat. 1; R45 May cause cancer.
Muta. Cat. 3; R68 Possible risk of irreversible effects.
3. Concentration range (%):
>= 7 - < 10
Classification:
Xn; R22 Harmful if swallowed.
T+; R26 Very toxic by inhalation.
R43 May cause sensitisation by skin contact.
Carc. Cat. 2; R45 May cause cancer.
Muta. Cat. 3; R68 Possible risk of irreversible effects.
Xi; R36/37/38 Irritating to eyes, respiratory system and skin.
4. Concentration range (%):
>= 5 - < 7
Classification:
Xn; R22 Harmful if swallowed.
T; R23 Toxic by inhalation.
R43 May cause sensitisation by skin contact.
Carc. Cat. 1; R45 May cause cancer.
Muta. Cat. 3; R68 Possible risk of irreversible effects.
Xi; R36/37/38 Irritating to eyes, respiratory system and skin.
5. Concentration range (%):
>= 3 - < 5
Classification:
Xn; R22 Harmful if swallowed.
T; R23 Toxic by inhalation.
R43 May cause sensitisation by skin contact.
Carc. Cat. 1; R45 May cause cancer.
Muta. Cat. 3; R68 Possible risk of irreversible effects.
6. Concentration range (%):
>= 1 - < 3
Classification:
T; R23 Toxic by inhalation.
R43 May cause sensitisation by skin contact.
Carc. Cat. 1; R45 May cause cancer.
Muta. Cat. 3; R68 Possible risk of irreversible effects.
7. Concentration range (%):
>= 0.1 - < 1
Classification:
Xn; R20 Harmful by inhalation.
Carc. Cat. 1; R45 May cause cancer.
Muta. Cat. 3; R68 Possible risk of irreversible effects.
8. Concentration range (%):
>= 0.01 - < 0.1
Classification:
Carc. Cat. 1; R45 May cause cancer.
Muta. Cat. 3; R68 Possible risk of irreversible effects.

Notes

Note E