Registration Dossier
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EC number: 500-097-4 | CAS number: 37353-75-6 1 - 4.5 moles propoxylated
Surface tension
Administrative data
Link to relevant study record(s)
- Endpoint:
- surface tension
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.5 (Surface Tension)
- Deviations:
- no
- GLP compliance:
- no
- Remarks:
- Conducted in a GLP compliant laboratory but not as part of a formal GLP study.
- Type of method:
- plate method
- Surface tension:
- 50.4 mN/m
- Temp.:
- 25 °C
- Conc.:
- 90 other: % saturation concentration
- Remarks on result:
- other: Mean of two tests (test 1 = 50.03 mN/m, test 2 = 50.73 mN/m).
- Conclusions:
- The surface tension of a 90% saturation concentration sample of test material was found to be 50.4 mN/m (mean). The test substance does not appear to be surface active i.e. surface tension <60 mN/m.
- Executive summary:
The surface tension of the test substance was determined in accordance with the EU Testing Method A.5, using the plate method. The surface tension of a 90% saturation concentration sample of test material was found to be 50.4 mN/m (mean). The test substance does not appear to be surface active i.e. surface tension <60 mN/m.
- Endpoint:
- surface tension
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Study period:
- 2010
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.5 (Surface Tension)
- Deviations:
- no
- GLP compliance:
- no
- Remarks:
- Conducted in a GLP compliant laboratory but not as part of a formal GLP study.
- Type of method:
- plate method
- Surface tension:
- 49.9 mN/m
- Temp.:
- 25 °C
- Conc.:
- 90 other: % of saturation concentration
- Remarks on result:
- other: Mean of two tests (Test 1 = 49.86 mN/m and test 2 = 49.97 mN/m)
- Conclusions:
- The surface tension of a 90% saturation concentration sample of test material was found to be 49.9 mN/m (mean). The test substance does not appear to be surface active i.e. surface tension <60 mN/m.
- Executive summary:
The surface tension of the test substance was determined in accordance with the EU Testing Method A.5, using the plate method. The surface tension of a 90% saturation concentration sample of test material was found to be 49.9 mN/m (mean). The test substance does not appear to be surface active i.e. surface tension <60 mN/m.
- Endpoint:
- surface tension
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.5 (Surface Tension)
- Deviations:
- no
- GLP compliance:
- no
- Remarks:
- Conducted in a GLP compliant laboratory but not as part of a formal GLP study.
- Type of method:
- plate method
- Surface tension:
- 47.2 mN/m
- Temp.:
- 25 °C
- Conc.:
- 90 other: % of saturation concentration
- Remarks on result:
- other: Mean of two tests (test 1 = 47.31 mN/m and test 2 = 47.05 mN/m)
- Conclusions:
- The surface tension of a 90% saturation concentration sample of test material was found to be 47.2 mN/m (mean). The test substance does not appear to be surface active i.e. surface tension <60 mN/m.
- Executive summary:
The surface tension of the test substance was determined in accordance with the EU Testing Method A.5, using the plate method and was reported as 47.2 mN/m (mean). The test substance does not appear to be surface active i.e. surface tension <60 mN/m.
Referenceopen allclose all
No significant ageing of the test substance was observed.
HPLC Analysis Results (corrected for appropriate dilution factor)
Test 1 90% saturation concentration: Peak 1 = 41 mg/l (equates to 46 mg/l in filtrate), Peak 2 = 9 mg/l (equates to 10 mg/l in filtrate) and Peak 3 = 16 mg/l (equates to 18 mg/l in filtrate).
Test 2 90% saturation concentration: Peak 1 = 41 mg/l (equates to 46 mg/l in filtrate), Peak 2 = 9 mg/l (equates to 10 mg/l in filtrate) and Peak 3 = 16 mg/l (equates to 18 mg/l in filtrate).
Peak 1 retention time: 6.6 mins
Peak 2 retention time: 8.7 mins
Peak 3 retention time: 9.2 mins
No significant ageing of the test substance was observed.
HPLC Analysis Results (corrected for appropriate dilution factor)
Test 1 90% saturation concentration: Peak 1 = 36 mg/l (equates to 40 mg/l in filtrate) and Peak 2 = 55 mg/l (equates to 61 mg/l in filtrate)
Test 2 90% saturation concentration: Peak 1 = 41 mg/l (equates to 46 mg/l in filtrate) and Peak 2 = 65 mg/l (equates to 72 mg/l in filtrate).
Peak 1 retention time: 6.3 mins
Peak 2 retention time: 6.6 mins
No significant ageing of the test substance was observed.
HPLC Analysis Results (corrected for appropriate dilution factor)
Test 1 90% saturation concentration: Peak 1 = 7 mg/l (equates to 8 mg/l in filtrate), Peak 2 = 9 mg/l (equates to 10 mg/l in filtrate) and Peak 3 = 6 mg/l (equates to 7 mg/l in filtrate).
Test 2 90% saturation concentration: Peak 1 = 8 mg/l (equates to 9 mg/l in filtrate), Peak 2 = 8 mg/l (equates to 9 mg/l in filtrate) and Peak 3 = 6 mg/l (equates to 7 mg/l in filtrate).
Peak 1 retention time: 9.8 mins
Peak 2 retention time: 14.1 mins
Peak 3 retention time: 19.9 mins
Description of key information
The surface activity determined in the key study was 50.4 mN/m. The substance does not appear to be surface active i.e. surface tension <60 mN/m.
Key value for chemical safety assessment
- Surface tension:
- 50.4
Additional information
Two studies were conducted on the registered substance to determine the surface tension of the substance, with an additional study conducted on the read-across substance BPA 2PO. All studies were conducted according to the EU Testing Method A. 5., and used the plate method. The key study on BPA 3PO gave a surface tension of 50.4 mN/m, the supporting study on the BPA 5PO gave a surface tension of 47.2 mN/m, and the read-across study on the BPA 2PO gave a surface tension of 49.9 mN/m. All the results are <60 mN/m which indicates that the substance is not likely to be surface active.
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