Registration Dossier
Registration Dossier
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EC number: 203-475-4 | CAS number: 107-25-5
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Meets scientific standards
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 005
Materials and methods
- Type of study / information:
- Occupational exposure measurements
- Endpoint addressed:
- not applicable
- Principles of method if other than guideline:
- Occupational monitoring
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Methyl vinyl ether
- EC Number:
- 203-475-4
- EC Name:
- Methyl vinyl ether
- Cas Number:
- 107-25-5
- Molecular formula:
- C3H6O
- IUPAC Name:
- methoxyethene
- Details on test material:
- no details
Constituent 1
Method
- Ethical approval:
- not applicable
- Details on study design:
- Personal monitoring was conducted for MVE between the years of 1982 and 2004 in the MVE manufacturing unit in South Charleston, WV and in the Specialty Products unit in Taft, LA. The objective was to evaluate potential exposures during various shifts and tasks for a variety of similar exposure groups.
- Exposure assessment:
- measured
- Details on exposure:
- Monitoring was performed for groups assessed to have potential for exposure to MVE for the purpose of applying exposure controls, assigning personal protective equipment, and verification of compliance with the company internal exposure guidelines.
Over the 22-year period, the exposure groups with potential for exposure consistently included outside and inside operators, one "weigh operator", maintenance personnel, Union rail tank car operators, and laboratory personnel.
Results and discussion
- Results:
- Results for all job assignments and tasks ranged from 0.001 ppm to 2.1 ppm, and the geometric mean for all exposures is 0.26 ppm (standard deviation 5.95 ppm), and the 95% upper confidence limit is 1.34 ppm.
Area emission monitoring results, although not indicative of personal exposure, were non-detected at the limit of quantitation (0.37-0.02 ppm).
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
