Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

OECD 308 sediment simulation testing has demonstrated that the DT50 (based on total radioactivity) in the sedment is >159d. Although the parent material appears to rapidly undergo changes and is no longer quantifiable. Radioactivity resulting from the parent in the form of bound residue and unknown degredation products have been concluded as persistant in the sediment. Some low level biodegradation (mineralization to CO2) was observed.

Additional information

An anaerobic degradation study in sediment using an EPA method provides reliable evidence of rapid (half life 4.3 days at 25ºC) primary anaerobic degradation.

A continuous activated sludge simulation study demonstrated 99.5 % of the test material in the influent was removed. 2% of the test material was lost to the air and 15.4% was adsorbed to the sludge. A total of 82.6 % biodegradation was measured after correction. The test material can therfore be expected to be significantly removed from industrial waste water streams during water treatment.

A Closed Bottle Test according to a slightly modified version of OECD 310 D test guideline (use of silca gel to increase bioavailability) and according to GLP was performed. 2% biodegradation was determined at day 28 and 37% at day 112. A MITI-I study was also available indicating 8-12 % biodegradation.

This substance is the main source material in a proposed family of Peroxyketal organic peroxides with very similar / identical properties. The justification for this approach has been attached in secton 13. The intention being facilitate the timely PBT / Ecotoxicity assessment of the other members of the group without uneccesary testing.