Registration Dossier
Registration Dossier
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EC number: 238-510-2 | CAS number: 14507-19-8
Endpoint summary
Administrative data
Description of key information
Additional information
No bioaccumulation data are available on lanthanum trihydroxide but literature data provide information on the soluble salt lanthanum nitrate. BCF values of 1.2-13.8 were recorded after 29-45days in; muscles skeleton and gills. Higher BCF values of 91-828 were recorded in internal organs. In all tissues equilibrium was reached or approached within the time period. Elimination in internal organs was shown to occur with a half life of 7 days. Lanthanum nitrate is therefore eliminated from fish and does not significantly bioaccumulate. The REACH criteria for PBT and vPvB as stated in Annex XIII give cut-off BCF values of 2000 and 5000 respectively and it is therefore considered reasonable to assume that lanthanum trihydroxide should not be considered to meet either of these criteria on the basis of the available data on an analogous substance. Furthermore being of very low water solublity it is expected to be less bioavailable than the soluble salt tested.
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