Registration Dossier
Registration Dossier
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EC number: 200-238-7 | CAS number: 55-56-1
Endpoint summary
Administrative data
Description of key information
Additional information
The available tests on Chlorhexidine biodegradability allow no clear conclusion about the rate of biodegradation. In a Closed-Bottle-Test no biodegradation was observed.
However, it has been demonstrated that some bacterial strains can grow in a medium containing Chlorhexidine. Several intermediates were identified as degradation metabolites. As most of the available studies used isolated bacteria strains and the tests were run under laboratory conditions, the results do not allow a classification of biodegradability or a conclusion about degradation rates in biological treatment plants and in environmental compartments. Furthermore, it remains unresolved if those metabolites of chlorhexidine biodegradation that are observed in laboratory tests are also formed in relevant amounts under more realistic STP conditions. However, no evidence exist that biodegradation under laboratory conditions will rely on different pathways than under STP conditions.
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