Registration Dossier
Registration Dossier
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EC number: 225-306-3 | CAS number: 4767-03-7
Endpoint summary
Administrative data
Description of key information
Bis-MPA is readily biodegradable and has a low log Kow (-1.1) indicating low adsorption and bioaccumulation potential. It is fully ionised in the aquatic environment at environmental pH, but not surface active. Based on read-across from a structurally similar substance 2,2-bis(hydroxymethyl)butanoic acid (CAS 10097-02-6)(BCF = 62 L/kg), it is concluded that Bis-MPA has low potential for bioaccumulation.
Additional information
Biodegradation: Bis-MPA is readily biodegradable according to a study to OECD guideline 301A.
Stability: In accordance with REACH Annex VIII column 2, the hydrolysis study does not need to be conducted as Bis-MPA is readily biodegradable.
Transport and distribution: According to Column 2 of Annex VIII of the REACH regulation, no adsorption / desorption study is required if a substance and its degradation products decompose rapidly.
Bioaccumulation: Based on read-across from a structurally similar substance 2,2-bis(hydroxymethyl)butanoic acid (CAS 10097-02-6)(BCF = 62 L/kg), it is concluded that Bis-MPA has low potential for bioaccumulation.
Simulation testing: In accordance with REACH Annex IX column 2, the degradation simulation testing in water and/or sediment and in soil do not need to be conducted as the substance is readily biodegradable.
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