Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 203-558-5 | CAS number: 108-18-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
More information will be discussed later based on ECHA communication/decision number CCH-D-2114521395-52-01/D
Additional information
Terrestrial fate
Volatilization of diisopropylamine from moist soil surfaces is not expected to be an important fate process since the cation will not volatilize. The potential for volatilization of diisopropylamine from dry soil surfaces may exist based upon a vapor pressure of 79.4 mm Hg at 25 deg C (Daubert TE, Danner RP; Physical and Thermodynamic Properties of Pure Chemicals Data Compilation Washington, DC: Taylor and Francis (1989)).
A determination of Koc has been determined using a calculation method developed for ionizable organic chemicals. A value of 66 has been obtained indicating that diisopropylamine is not expected to sorb on soil particles.
Aquatic fate
Volatilization from water surfaces is not expected to be important fate process since the protonated form is not expected to volatilize at environmental pH.
Atmospheric fate
According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere (Bidleman TF; Environ Sci Technol 22: 361-367 (1988)), diisopropylamine, which has a vapor pressure of 79.4 mm Hg at 25 deg C, is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase diisopropylamine is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 4 hours, from its rate constant of 9.7*10 -11 cm3/molecule-sec at 25 deg C (Meylan WM, Howard PH; Chemosphere 26: 2293-99 (1993)). Diisopropylamine is not expected to directly photolyze due to the lack of absorption in the environmental UV spectrum.
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