Registration Dossier
Registration Dossier
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EC number: 219-147-9 | CAS number: 2373-38-8
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Reference
Description of key information
Key value for chemical safety assessment
Additional information
The substance CAS 2373-38-8 was evaluated as part of the compliance check procedure for which a final decision with the decision number CCH-D-2114489558-27-01/F was released by ECHA in November 2019. In the decision, registrants were required to provide short-term aquatic toxicity data by 22 August 2022 and long-term aquatic toxicity data (including aquatic invertebrate toxicity data) by 21 May 2024. In the previous version of the technical dossier, a read-across from docusate sodium (CAS 577-11-7) - for which a long-term toxicity data exists on Daphnia magna - was used as key information in the dossier of the substance (CAS 2373-38-8. In the final decision released, ECHA disagreed to use the read across data from docusate sodium as key information. The data from docusate sodium will now only be used as supporting information. New chronic aquatic invertebrate toxicity data will be presented in a subsequent dossier update, by 21 May 2024 at the latest, and evaluated in a group approach. Besides, until new aquatic chronic toxicity data become available, the derivation of PNEC values will be based on a conservative approach using the acute aquatic data on the substance CAS 2373-38-8 in combination with an AF of 1000 for freshwater and 10000 for marine water.
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