Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: US EPA accepted QSAR method for organic chemicals properties assessment
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2009

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: QSAR
Principles of method if other than guideline:
ECOSAR
Program
(v1.00)
GLP compliance:
no
Remarks:
not applicable to QSAR models

Test material

Constituent 1
Chemical structure
Reference substance name:
Trichloroethylene
EC Number:
201-167-4
EC Name:
Trichloroethylene
Cas Number:
79-01-6
Molecular formula:
C2HCl3
IUPAC Name:
trichloroethylene

Results and discussion

Any other information on results incl. tables

Sublethal observations / clinical signs:

Overview of QSARs estimations on short-term aquatic toxicity of trichloroethylene to fish

 

Method

 

Results

Remarks

Reference

QSAR

estimate

Vinyl/Allyl Halides:

Fish, 96-hr LC50 =11.210 mg/L (ppm)

 

Fish (SW), 96-hr LC50 =9.646 mg/L (ppm)

 

Neutral Organic SAR (Baseline Toxicity):

 

Fish, 96-hr LC50 =40.265 mg/L (ppm)

Reliable with

restrictions,

QSAR estimated

data

ECOSAR

Program

(v1.00)

Applicant's summary and conclusion