Registration Dossier

Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994
Report Date:
1994

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 405 (Acute Eye Irritation / Corrosion)

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals / tissue source

Species:
rabbit
Strain:
New Zealand White

Results and discussion

In vivo

Resultsopen allclose all
Irritation parameter:
cornea opacity score
Basis:
mean
Time point:
other:
Score:
0
Max. score:
0
Irritation parameter:
iris score
Basis:
mean
Time point:
other:
Score:
0
Max. score:
1
Reversibility:
fully reversible within:
Irritation parameter:
conjunctivae score
Basis:
mean
Time point:
other:
Score:
> 0.3 - < 0.7
Max. score:
2
Reversibility:
fully reversible within:
Irritation parameter:
chemosis score
Basis:
mean
Time point:
other:
Score:
> 0.3 - < 0.7
Max. score:
2
Reversibility:
fully reversible within:

Applicant's summary and conclusion