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Toxicity to microorganisms

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Description of key information

EC50 (3 h) > 100 mg/L (OECD 209)

Key value for chemical safety assessment

Additional information

The toxicity of 2-methyl-N-(4-sulfamoylphenyl) prop-2-enamide (SPM-N) to aquatic microorganisms was investigated in a study by Desmares-Koopmans (2007b). This test was performed according to OECD Guideline 209 (1984) under GLP conditions. Activated sludge microorganisms (from a predominantly domestic sewage) were exposed to the test substance for 3 hours at 19 ± 1 °C under continuous stirring and aeration. After the exposure period, no significant effects on respiration rate (measured as O2 consumption in the test vessels) were reported, and therefore the EC50 (3 h) was determined to be > 100 mg/L (nominal concentration).

The biodegradation test performed with this substance (Desmares-Koopmans, 2007a; see IUCLID section 5.2.1) also showed that SPM-N is not inhibitory to aquatic microorganisms (biodegradation in the toxicity control 35% after 14 days).

In conclusion, SPM-N is not inhibitory to activated sludge microorganisms activity.