Registration Dossier
Registration Dossier
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EC number: 222-960-1 | CAS number: 3681-71-8
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Documentation insufficient for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 974
- Report date:
- 1974
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- GLP compliance:
- no
- Remarks:
- Study predates GLP
- Test type:
- other: no data
- Limit test:
- yes
Test material
- Reference substance name:
- (Z)-hex-3-enyl acetate
- EC Number:
- 222-960-1
- EC Name:
- (Z)-hex-3-enyl acetate
- Cas Number:
- 3681-71-8
- Molecular formula:
- C8H14O2
- IUPAC Name:
- (Z)-hex-3-enyl acetate
- Details on test material:
- - Name of test material (as cited in study report): RIFM 74-59, cis-3-hexenyl acetate
- Substance type: no data
- Physical state: no data
- Analytical purity: no data
- Impurities (identity and concentrations): no data
- Composition of test material, percentage of components: no data
- Isomers composition: no data
- Purity test date: no data
- Lot/batch No.: no data
- Expiration date of the lot/batch: no data
- Stability under test conditions: no data
- Storage condition of test material: no data
- Other: no data
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Doses:
- 5 g/kg body weight
- No. of animals per sex per dose:
- 10/ dose
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 5 other: g/kg
- Mortality:
- None.
- Other findings:
- Symptomatology: None
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The test substance was assessed for acute toxicity via the dermal route and was found to have an LD50 of greater than 5 g/kg. As such, the test substance is not considered to be acutely toxic by the dermal route.
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