Registration Dossier

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

None of the in-vitro tests revealed a mutagenic potential of the test substance. It can therefore be concluded that the substance is non mutagenic in-vitro, and possible in vivo.

Short description of key information:
In-vitro: negative in Ames Test with Salmonella typhimurium strains TA1535, TA1537, TA98 and TA100 and Escherichia coli strain WP2uvrA (with and without metabolic activation)
in-vitro: negative in Chromosome-Aberration in Chinese Hamster Lung (CHL) cell line (CHL/IU)
in-vitro: negative in Mouse Lymphoma Assay

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

There are conclusive but not sufficient data to classify the substance with regard to mutagenicity. The test substance is not classified for this endpoint in accordance to Directive 67/548/EEC or the CLP Regulation (EC) No 1272/2008.