Alkenes, C11-12, hydroformylation products, distn. residues

Water solubility

Administrative data

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2010-03-24 to 2010-04-26

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: GLP Guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2010

Report date:

2010

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7840 (Water Solubility)

Deviations:

no

GLP compliance:

yes

Type of method:

flask method

Test material

Test material information

Constituent 1

Reference substance name:

Alkenes, C11-12, hydroformylation products, distn. residues

EC Number:

292-427-6

EC Name:

Alkenes, C11-12, hydroformylation products, distn. residues

Cas Number:

90622-27-8

Molecular formula:

not available; UVCB

IUPAC Name:

Alkenes, C11-12, hydroformylation products, distn. residues

Details on test material:

Name of test material (as cited in study report): Alkenes, C11-12, hydroformylation products, distn. residues
- Substance type: pure Active Substance
- Physical state: liquid
- Storage condition of test material: Ambient condition in the dark

Results and discussion

Water solubility

Water solubility:

10.8 mg/L

Temp.:

20 °C

pH:

7.35

Remarks on result:

other: +/- 0.5 mg/L, CV = 5.0 %

Details on results:

The limit of quantification (LOQ) for the determination of test substance in reagent water was defined as 1.90 mg/L, calculated as the sum of the concentration of the lowest-level calibration standard (1.00 mg C/L) and the overall mean background in the reagent blank sample (0.495 mg C/L) divided by the %C in the test substance (78.68 %).

Any other information on results incl. tables

Table: Water solubility of the test substance at 20 °C
Sample	Sampling Interval [h]	Measured [mg C/L]	Background corrected result [mg/L]	Analytical result {mg/L]	Mean analytical result ± SD [mg/L]	% Difference
1	24	10.9	10.4	13.2	13.1 ± 0.8 (CV = 6.0%)
	24	11.4	10.9	13.9
	24	10.2	9.68	12.3
2	48	9.69	9.2	11.7	11.1 ± 058 (CV = 4.6%)	17
	48	8.99	8.5	10.8
	48	8.99	8.5	10.8
3	72	9.08	8.58	10.9	10.5 ± 0.4 (CV = 3.8%)	5.9
	72	8.57	8.07	10.3
	72	8.52	8.03	10.2
Overall mean =				10.8
SD =				0.5
CV =				5%
N =				6

SD = standard deviation; CV = coefficient of variation; N = Number of measurements

Background corrected result (mg C/L) = Measured result (mg C/L) - overall mean of the reagent blank (0.495 mg C/L)

Analytical result = Background corrected result (mg C/L) / %C in test substance (78.68%)

Applicant's summary and conclusion

Conclusions:

Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility of Alkenes, C11-12, hydroformylation products, distn. residues was determined in reagent water at 20 °C using the shake flask method. Solubility samples were collected and analysed using total carbon analysis (TOC). The mean net (background subtracted) solubility (n = 6) of the test substance at 20°C was 10.8 mg/L ± 0.5 mg/L (CV = 5.0 %)

Executive summary:

The water solubility of Alkenes, C11 -12, hydroformylation products, distn. residues was determined in reagent water at 20 °C using the shake flask method according to OECD Guideline of Testing of Chemicals No. 105: "Water Solubility". Solubility samples were collected and analysed using total carbon analysis (TOC). The mean net (background subtracted) solubility (n = 6) of the test substance at 20°C was 10.8 mg/L ± 0.5 mg/L (CV = 5.0 %)