Registration Dossier

Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
review article or handbook
Title:
Assessment of structurally related chemicals: toxicity and ecotoxicity of acrylic acid and acrylic acid alkyl esters (acrylates), methacrylic acid and methacrylic acid alkyl esters (methyacrylates).
Author:
Greim H et al.
Year:
1995
Bibliographic source:
Chemosphere 31(2): 2637-2659

Materials and methods

Type of study / information:
Review
Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
BUA compiled the available data on toxicity and ecotoxicity for several acrylic and methacrylic acid esters and their corresponding acids.

Test material

Constituent 1
Chemical structure
Reference substance name:
tert-butyl acrylate
EC Number:
216-768-7
EC Name:
tert-butyl acrylate
Cas Number:
1663-39-4
Molecular formula:
C7H12O2
IUPAC Name:
tert-butyl acrylate

Results and discussion

Any other information on results incl. tables

The available data on toxicity and ecotoxicity for several acrylic and methacrylic acid esters and their corresponding acids indicates a qualitative similarity in the toxicological and ecotoxicological properties of the compounds considered. The data indicate that methacrylates are less reactive than the corresponding acrylates.

Applicant's summary and conclusion