Registration Dossier

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study according to international accepted guidelines but not GLP compliant.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report Date:
2013

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
ASTM E537-98 (Newer version of ASTM E537-76)
Deviations:
no
GLP compliance:
no
Type of method:
thermal analysis
Remarks:
derivatography

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
Test item: Tryptamine
CAS No.: 61-54-1
Batch No.: S37020N
Physical state: solid, amorphous powder
Colour: yellowish-brown
Storage: 8-15 °C, protected from light and moisture

Results and discussion

Melting / freezing point
Melting / freezing pt.:
116 °C
Atm. press.:
ca. 101 kPa
Decomposition:
yes
Remarks:
Mild exothermic process starts at 164°C and it has a peak at 224°C with 7% weight loss. The weight loss is more than 17% up to 250°C
Sublimation:
no

Applicant's summary and conclusion

Conclusions:
The melting point of tryptamine is 116°C.