Registration Dossier

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Report Date:
1953
Reference Type:
study report
Title:
Unnamed
Report Date:
1951

Materials and methods

Principles of method if other than guideline:
other: BASF-test
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
IUCLID4 Test substance: as prescribed by 1.1 - 1.4

Test animals

Species:
mouse

Administration / exposure

Route of administration:
subcutaneous
Vehicle:
water
Doses:
0.25, 0.5, 1.0, 2.0 and 4.0 cm3/kg (ca. 260, 520, 1040, 2080 and 4160 mg/kg bw)
No. of animals per sex per dose:
1 (2080 and 4160 mg/kg bw)
5 (260, 520 and 1040 mg/kg bw)
Control animals:
no

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
ca. 750 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion