Registration Dossier
Registration Dossier
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EC number: 429-370-5 | CAS number: 220410-74-2
Endpoint summary
Administrative data
Description of key information
Additional information
Short-Term toxicity to fish
The purpose of this study according to OECD TG 203 was to estimate the acute toxicity of the test item to rainbow trout (Oncorhynchus mykiss) under static test conditions. The 96-hour LC50 value for the test item and rainbow trout was empirically estimated to be >100 mg a.i./L. The No-Observed-Effect Concentration (NOEC) was established to be 100 mg a.i./L.
Short-Term toxicity to aquatic invertebrates
The purpose of this study according to OECD TG 202 was to estimate the acute toxicity (EC50) of the test item to daphnia {Daphnia magna) under static test conditions. The 48-hour EC5O was calculated by probit analysis to be 570 mg a.i/L with 95% confidence limits of 490 and 680 mg a.i./L. The No-Observed-Effect Concentration (NOEC) was determined to be 260 mg a.i./L.
Short-Term toxicity to algae and cyanobacteria
The purpose of this study according to OECD TG 201A adopted 1984-07-06 was to determine the effect of the test item on the growth of the freshwater green alga, Pseudokirchneriella subcapitata (formerly Selenastrum capricornutum). No-Observed-Effect Concentration (NOEC) was empirically estimated to be 74 mg a.i./L where a 2.3% reduction in growth rate relative to the control was observed. The 72-hour ErC50 was calculated to be 380 mg a.i./L (corresponding 95% confidence limits of 110 to 1400 mg a.i./L).
Short-Term toxicity to microorganism
The objective of this study according to OECD TG 209 was to determine the effect of different concentrations of the test item on sewage microorganisms by measuring the respiration rate under defined conditions. The EC50 value was calculated to be 1520 mg/L with 95% confidence intervals of 960 to 2430 mg/L. The EC50 value for 3,5-dichlorophenol was calculated to be 15 mg/L, which was within the acceptable limits,(5.0 to 30 mg/L) as specified in OECD 209 Guideline. Thus, all validation criteria were fulfilled
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