Registration Dossier

Diss Factsheets

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
15 June 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study was well conducted according to guidelines and critical micelle concentration (CMC) method is used as an alternative to the water solubility.
Qualifier:
according to guideline
Guideline:
other: DIN 53914 determining the surface tension of surfactants
Principles of method if other than guideline:
For surface active substances the critical micelle concentration (CMC) method is used as an alternative to the water solubility. The critical micelle concentration (CMC) is determined by measuring the surface tension of test substance solutions at different test substance concentration. For surface active substances which form micelles in solution, the surface tension decreases with increasing concentration until the CMC is reached. At concentrations above the CMC, the surface tension remains constant. The CMC is determined from a plot of the surface tension versus the logarithm of the test substance concentration.

GLP compliance:
no
Type of method:
other: critical micelle concentration (CMC)
Key result
Water solubility:
0.14 g/L
Temp.:
25 °C
pH:
7
Remarks on result:
other: critical micelle concentration (CMC)
Conclusions:
Under the study conditions, the water solubility (critical micelle concentration) of the test substance was determined to be 0.14 g/L or 140 mg/L at 25°C (moderately soluble).
Executive summary:

The water solubility of the test substance, C16-18 and C18-unsatd. TMAC (purity not specified) was determined using a critical micelle concentration (CMC) method according to DIN 53914 Guideline. Under the study conditions, the water solubility (critical micelle concentration) of the test substance was determined to be 0.14 g/L or 140 mg/L at 25°C (Borjesson, 2012).

.

Description of key information

The water solubility of the test substance was determined using the critical micelle concentration (CMC) method according to DIN 53914 Guideline (Börjesson, 2012).

Key value for chemical safety assessment

Water solubility:
140 mg/L
at the temperature of:
25 °C

Additional information

(moderately soluble)