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Physical & Chemical properties

Partition coefficient

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Description of key information

LogPow= >3.5 at 25°C, estimated based on individual solubility

LogPow= 10.7 at 25°C, estimated using KOWWIN

Key value for chemical safety assessment

Log Kow (Log Pow):
10.7
at the temperature of:
25 °C

Additional information

The estimation was based individual solubility and based on theoretical fragmentation of the molecule using KOWWIN Version 1.6.

Neither the HPLC-method according to OECD Guideline No. 117 nor the flask-shaking method according to OECD Guideline No. 107 were applicable for the determination of the partition coefficient of test item. Thus, the log Pow-value for the test item was estimated by a model calculation.

The estimation of the partition coefficient of test item by a model calculation based theoretical fragmentation of the molecule into suitable substructures for which reliable Log Pow increments are known, seems to be more reliable. The Log Pow was obtained by summing the fragment values and the correction terms.