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EC number: 240-183-6 | CAS number: 16040-69-0
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to aquatic invertebrates
Key value for chemical safety assessment
Additional information
To assess the toxicity of CAS 16040 -69 -0 to aquatic invertebrates, read across was performed to structural analogue substances.
The toxicity of the analogue CAS 147-14-8 to Daphnia magna was tested in a study following EU Directive 79/831/EEC. The animals were exposed to the test substance for 48 hours and an EC50 >500 mg/l was determined (BASF AG 1989). However, a solubiliser was used in this test. The result is supported by two further studies on CAS 147-14-8 conducted in compliance with EEC Directive 93/32/EEC. In both studies an EC50 (48h) >100 mg/l was determined (BASF AG 2001, 2004).
The results of two further tests conducted with the structural similar substance CAS 1328-53-6 are comparable to the data obtained for the analogue CAS 147-14-8. The toxic effect of the substance on D. magna was investigated in a study following directive 84/449/EEC, C.2. The test substance was dissolved in the test water by using a solubiliser. After 48 hours the test was terminated and an EC50 (48h) of >500 mg/l was detected (BASF AG 1988). Corresponding data were collected by a study following US EPA guideline EPA-660/3-75-009 determining an EC50 of 153.6 mg/l (Union Carbide Corporation 1978).
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