Tin disulphide

Sediment toxicity

Administrative data

Endpoint:

sediment toxicity: short-term

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference

Reference Type:

publication

Title:

A comparative study of the toxicity and inhibitory effects of inorganic tin compounds on various biological subjects

Author:

Fargasova, Agata

Year:

1994

Bibliographic source:

Biologia (Bratislava) 49(3): 307-311

Materials and methods

Test guideline

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 235 (Chironomus sp., Acute Immobilisation Test)

Deviations:

no

Remarks:

Test duration extended to 96 hours, use of Tubifex tubifex

GLP compliance:

no

Test material

Test material information

1

Reference substance name:

Tin dichloride

EC Number:

231-868-0

EC Name:

Tin dichloride

Cas Number:

7772-99-8

Molecular formula:

Cl2Sn

Details on test material:

SnCl2*2H2O p.a. from Lachema, Brno, Czech Republic

Specific details on test material used for the study:

SnCl2*2H2O p.a. from Lachema, Brno, Czech Republic

Sampling and analysis

Analytical monitoring:

not specified

Test substrate

Vehicle:

no

Test organisms

Test organisms (species):

Tubifex tubifex

Study design

Study type:

laboratory study

Test type:

static

Water media type:

freshwater

Type of sediment:

not specified

Remarks:

none

Limit test:

no

Test conditions

Test temperature:

20°C

Details on test conditions:

TEST SYSTEM
- Test container (material, size): dish
- Sediment volume: none
- Overlying water volume: 20 mL
- Aeration: no

EXPOSURE REGIME
- Feeding regime: no feeding


OTHER TEST CONDITIONS
- Light quality: without direct sunlight

VEHICLE CONTROL PERFORMED: no

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

48 h

Dose descriptor:

LC50

Effect conc.:

54.9 mg/L

Nominal / measured:

nominal

Conc. based on:

element

Remarks:

tin(II) moiety

Basis for effect:

mortality

Effect concentrations 2

Key result

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

30 mg/L

Nominal / measured:

nominal

Conc. based on:

element

Remarks:

tin(II) moiety

Basis for effect:

mortality

Details on results:

LC50: 30.0 mg Sn/L (95% C.I.: 24.0-32.8 mg Sn /L)

Reported statistics and error estimates:

probit analysis

Applicant's summary and conclusion

Validity criteria fulfilled:

not specified

Conclusions:

Tubifex tubifex 96h-LC50: 30.0 mg/L

Executive summary:

In an acute study, the acute toxicity of tin dichloride on Tubifex tubifex has been determined by Fargasova (1994). The test was performed similar to OECD 235. The result was based on dissolved tin ions. The 96-hour LC50 based on tin(II) is 30.0 mg/L.