Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

The assessment of the aquatic toxicity of the registration is based on data from three trophic levels.

The LC50 value of the test substance to Oncorhynchus mykiss was determined to be 3.8 mg/L in a GLP guideline study according to OECD 203 (BASF AG 12F0230/985046, 1998) under flow-through conditions. This value is supported by the result of another GLP guideline study according to OECD 203 with Brachydanio rerio under a static exposure regime which revealed a LC50 value greater than 2.2 and lower than 4.6 mg/L (BASF 17F0246/925043, 1993).

The result of a flow-through exposure test on Daphnia magna according to OECD 202 revealed an acute EC50 (48h) greater than 100 mg/L (BASF AG 98/0634/53/1, 1998).

According to the REACH legislation, long-term aquatic toxicity testing is indicated in case the chemical safety assessment raises concerns. For the registration item,  a risk assessment covering all relevant exposures throughout the complete life cycle has been performed, demonstrating the absence of a risk to the environment. Therefore, chronic aquatic studies in fish and daphnia are deemed not required to ensure safe use of the material.

The result of a static exposure test on Scenedesmus subspicatus according to OECD 201 determined an acute EC50 (96h) from 27 mg/L for growth rate and an EC10 (growth rate, 72h) value of 8.97 mg/L (BASF AG 98/0634/60/1, 1998).

No data on the toxicity of the test substance to microorganisms are available. Based on its molecular structure, the test substance is considered to be similar to CAS 195008-76-5 and CAS 173011-06-8. Therefore, the EC20 = ca. 1000 mg/L of CAS 173011-06-8 determined in a study according to OECD 209 was applied to cover this endpoint (BASF AG 92/1991/08/1, 1992). Based on these data, the inhibition of the degradation activity of activated sludge is not expected to be anticipated when introduced in appropriate concentrations.

Additional information