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EC number: 202-870-9 | CAS number: 100-61-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Remarks:
- Study well documented, meets generally accepted principles of measurement of biodegradation using a method different from those recommended by international guidelines.
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 986
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- yes
- Remarks:
- Use of an automated headspace method.
- Principles of method if other than guideline:
- A chemical control was tested simultaneously in a biodegradation test with activated sludge to determine degradation in the absence of inoculum. In fact this control evaluates the hydrolytical stability of the test substance under the test conditions applied.
- GLP compliance:
- no
Test material
- Reference substance name:
- N-methylaniline
- EC Number:
- 202-870-9
- EC Name:
- N-methylaniline
- Cas Number:
- 100-61-8
- Molecular formula:
- C7H9N
- IUPAC Name:
- N-methylaniline
Constituent 1
- Radiolabelling:
- no
Study design
- Analytical monitoring:
- yes
- Details on sampling:
- Samples had been acidified by injection of 0.5 ml 2 N phosphoric acid and filtered through 0.22-pm membrane filters prior to analysis.
- Buffers:
- Not applicable.
- Estimation method (if used):
- Not applicable.
Duration of test
- Duration:
- 21 d
- Initial conc. measured:
- 20 mg/L
- Number of replicates:
- 3 for each time point.
- Positive controls:
- no
- Negative controls:
- no
- Statistical methods:
- Not applied.
Results and discussion
- Preliminary study:
- Not applicable.
- Test performance:
- The results refer to abiotic degradation, which may include hydrolysis, but determaination of hydrolysis was not the ultimate endpoint of the experiment.
- Transformation products:
- no
Total recovery of test substance (in %)
- % Recovery:
- ca. 92
- pH:
- 7
- Temp.:
- 25 °C
- Duration:
- 21 d
Dissipation DT50 of parent compound
- Key result
- pH:
- 7
- Temp.:
- 25 °C
- Remarks on result:
- other: the test substance was not degraded under the test conditions
Applicant's summary and conclusion
- Conclusions:
- The test substance showed no significant abiotic degradation in water during 21 days of exposure at pH of 7.0 ± 0.2 and a temperature of 25 ± 2 °C.
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