1-Propanaminium, N,N,N-trimethyl-3-(octadecyloxy)-, chloride (1:1)

Surface tension

Administrative data

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

12, 18, 20 September 2007

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results.

Cross-reference

Reason / purpose for cross-reference:

reference to other study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2007

Report date:

2007

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Deviations:

yes

Test guideline 2

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Deviations:

yes

Test guideline 3

Qualifier:

according to guideline

Guideline:

other: ISO 304

Deviations:

no

Principles of method if other than guideline:

The surface tension result was not corrected using the Harkins-Jordan correction table as the correction is not applicable to the apparatus used. Once calibrated, the balance and ring assembly used in this test give a direct reading for surface tension that is within the required accuracy (± 0.5 mN/m); this is as a result of the reduced ring dimensions.
This deviation has been considered not to have affected the integrity of the study.

GLP compliance:

yes (incl. QA statement)

Remarks:

Date of inspection: 30 August 2005 Date of Signature: 21 November 2005

Type of method:

ring method

Test material

Test material information

Constituent 1

Reference substance name:

trimethyl[3-(octadecyloxy)propyl]azanium chloride

EC Number:

700-414-8

Cas Number:

23328-71-4

Molecular formula:

C24H52ClNO

IUPAC Name:

trimethyl[3-(octadecyloxy)propyl]azanium chloride

Constituent 2

Reference substance name:

1-Propanaminium, N,N,N-trimethyl-3-(octadecyloxy)-, chloride

IUPAC Name:

1-Propanaminium, N,N,N-trimethyl-3-(octadecyloxy)-, chloride

Details on test material:

- Name of test material (as cited in study report): 3-Octadecyloxypropyl-N,N,N-trimethylammonium chloride
- Molecular formula (if other than submission substance): Not applicable
- Molecular weight (if other than submission substance): Not applicable
- Smiles notation (if other than submission substance): Not applicable
- InChl (if other than submission substance): Not applicable
- Structural formula attached as image file (if other than submission substance): Not applicable
- Substance type: white solid
- Physical state: solid
- Analytical purity: Not reported
- Impurities (identity and concentrations): Not reported
- Composition of test material, percentage of components: Not reported
- Isomers composition: Not reported
- Purity test date: Not reported
- Lot/batch No.: Exp. I-070518
- Expiration date of the lot/batch: Not reported
- Radiochemical purity (if radiolabelling): Not applicable
- Specific activity (if radiolabelling): Not applicable
- Locations of the label (if radiolabelling): Not applicable
- Expiration date of radiochemical substance (if radiolabelling): Not applicable
- Stability under test conditions: Not reported.
- Storage condition of test material: room temperature in the dark
- Other: Not reported.

Results and discussion

Surface tension

Surface tension:

42.1 mN/m

Temp.:

22 °C

Conc.:

1.07 g/L

Any other information on results incl. tables

Calibration factor (f)

The readings, temperatures and the corresponding calibration factors for glass double-distilled water are shown in the following table:

Reading (mN/m)	Temperature (ºC)	Literature Value (mN/m)	Calibration Factor
72.5	22.0	72.41	0.999
72.5	22.0	72.41	0.999
72.5	22.0	72.41	0.999
72.5	22.0	72.41	0.999
72.5	22.0	72.41	0.999
72.5	22.0	72.41	0.999
Mean Calibration Factor = 0.999

Sample solution readings

The readings, times and temperatures for the sample solution are shown in the following table:

Time (mins)	Reading (mN/m)	Temperature (ºC)
80	42.5	22.0
90	42.0	22.0
105	42.0	22.0
115	42.0	22.0
130	42.0	22.0

Mean reading                    :   42.1 mN/m
Surface tension                  = reading x calibration factor
                                         = 42.1 x 0.999
                                         = 42.1 mN/m
Temperature                      :   22.0 ± 0.5ºC
pH of sample solution        :   5.2

Discussion

Substances showing a surface tension lower than 60 mN/m should be regarded as being surface‑active.

It is evident from the information obtained in the hydrolysis test (5.1.2 Hydrolysis) and data relating to the pH of the test material in water that negligible hydrolysis of the sample solution occurred during the course of the surface tension test.

As a result of 42.1 mN/m was obtained, the test material was regarded as a classic surfactant. Additionally the test material had a structure which was typical of a surfactant (polar head with carbon tail).

For additional information, a solution of test material (~10 g/l) in water saturated n-octanol was partitioned with an equal amount of n-octanol saturated water. Observations after this test showed that the two immiscible phases emulsified fully and no separation was evident.

Applicant's summary and conclusion

Conclusions:

The surface tension of a 1.07 g/l solution of test material has been determined to be 42.1 mN/m at 22.0 ± 0.5°C. The test material is considered to be a surface-active material.

Executive summary:

Surface Tension. 42.1 mN/m (1.07 g/l solution) at 22.0 ± 0.5°C, using a ring method based on ISO 304, Method A5 of Commission Directive 92/69/EEC and Method 115 of the OECD Guidelines for Testing of Chemicals, 27 July 1995. The test material is considered to be a surface-active material.