Registration Dossier
Registration Dossier
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EC number: 238-969-9 | CAS number: 14901-07-6
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- DPIM: IFX000
- Author:
- Richard J. Lewis, Sr.
- Year:
- 2 007
- Bibliographic source:
- SAX (Sax's Handbook of Dangerous Industrial Materials);Food and Cosmetics Toxicology. 2 (1964), 327.
- Reference Type:
- review article or handbook
- Title:
- DOSE ID.: I58
- Author:
- RSC Publishing
- Year:
- 2 011
- Bibliographic source:
- Dictionary of Substances and their effects (DOSE);Food Cosmet. Toxicol. 1964, 2, 327
- Reference Type:
- other: Authoritative data base
- Title:
- GCID : 93884
- Author:
- ACToR database
- Year:
- 2 011
- Bibliographic source:
- ACToR (Aggregated Computational Toxicology Resource);Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.
- Reference Type:
- review article or handbook
- Title:
- Chapman & Hall Number: KCN48-Y
- Author:
- Chapman & Hall
- Year:
- 2 012
- Bibliographic source:
- Combined Chemical Dictionary, Version 6.1
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- standard acute method
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- 4-(2,6,6-trimethylcyclohex-1-ene-1-yl)-but-3-ene-2-one
- EC Number:
- 238-969-9
- EC Name:
- 4-(2,6,6-trimethylcyclohex-1-ene-1-yl)-but-3-ene-2-one
- Cas Number:
- 14901-07-6
- Molecular formula:
- C13H20O
- IUPAC Name:
- 4-(2,6,6-trimethylcyclohex-1-en-1-yl)but-3-en-2-one
- Test material form:
- other: oily liquid
- Details on test material:
- - Name of test material (as cited in study report): 4-(2,6,6-trimethylcyclohex-1-ene-1-yl)-but-3-ene-2-one
- Substance type: Organic
- Physical state: liquid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 4 590 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The lethal dose value (LD50) causing acute oral toxicity to Rat is 4590 mg/kg. This value indicate that 4-(2,6,6-trimethylcyclohex-1-ene-1-yl)-but-3-ene-2-one is non toxic to Rat by oral route.
- Executive summary:
The lethal dose value (LD50) causing acute oral toxicity to Rat is 4590 mg/kg. This value indicate that 4-(2,6,6-trimethylcyclohex-1-ene-1-yl)-but-3-ene-2-one is non toxic to Rat by oral route.
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