Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

42d NOEC (Pimephales promelas; mortality and growth) >= 1.357 mg/L (measured concentration)

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
1.357 mg/L

Additional information

Since no reliable chronic fish test is available for C12AS Li (CAS 2044-56-6), in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 a read-across to another structurally related category member was conducted. Read-across data from another C12 homologue - C12AS Na (CAS 151-21-3) were used. As the toxicity of alkyl sulfates is dependent on the carbon chain length, it is expected that the toxic effects are comparable for all the C12 homologues and the influence of the counter ion can be neglected.

A 42-day flow-through study with fathead minnow (Pimephales promelas) examining the toxic effect of CAS 151-21-3 is available (Belanger et al. 1995). Juvenile mortality and juvenile growth were determined in a non-GLP test after exposure to five concentrations up to 1.357 mg/L (measured concentration, equal to 2.1 mg/L of nominal concentration). Since no adverse effects were observed regarding fish survival and body weight, the NOEC was determined as 1.357 mg/L (measured concentration).

Due to structural and property similarities with the tested category member, it can be concluded that the above results apply also to C12AS Li (CAS 2044-56-6).