Registration Dossier
Registration Dossier
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EC number: 204-436-4 | CAS number: 120-93-4
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
Due to the measured and calculated Koc values the substance is not supposed to strongly bind to solid soil phase. Hence, adsorption is not an important fate path in the environment.
Key value for chemical safety assessment
- Koc at 20 °C:
- 19
Additional information
A GLP test according to OECD guideline 106 using 4 different soils was performed applying radioactive material for detection (BASF, 295/162-D2149, 2003). Koc were estimated to be in the range of 4 -19 for all soils. This result is supported by a calculation using EpiSuite v4.11 (BASF, 2017). Using the molecular connectivety index (MCI) method, the Koc was calculated to be 4.776 L/kg (log Koc=0.6791). With the Kow method a Koc of 1.697 L/kg (log Koc= 0.2297) was calculated.
Based on measured and calculated Koc values, adsorption to the soil phase is not expected for the test substance (log Koc < 3).
QSAR-disclaimer
In Article 13 of Regulation (EC)
No 1907/2006, it is laid down that information on intrinsic properties
of substances may be generated by means other than tests, provided that
the conditions set out in Annex XI (of the same Regulation) are met.
Furthermore according to Article 25 of the same Regulation testing on
vertebrate animals shall be undertaken only as a last resort.
According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can
be used if (1) the scientific validity of the (Q)SAR model has been
established, (2) the substance falls within the applicability domain of
the (Q)SAR model, (3) the results are adequate for the purpose of
classification and labeling and/or risk assessment and (4) adequate and
reliable documentation of the applied method is provided.
For the assessment of 2-Imidazolidone (Q)SAR results were used for
adsorption/desorption. The criteria listed in Annex XI of Regulation
(EC) No 1907/2006 are considered to be adequately fulfilled and
therefore the endpoint(s) sufficiently covered and suitable for risk
assessment.
Therefore, further experimental studies on adsorption/desorption are not
provided.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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