Registration Dossier
Registration Dossier
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EC number: 309-712-9 | CAS number: 100684-39-7 A complex combination of hydrocarbons obtained as a residue from the distillation of crude oil under vacuum. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range above C50 and boiling in the range above approximately 360°C (680°F).
Developmental toxicity / teratogenicity
Administrative data
- Endpoint:
- developmental toxicity
- Type of information:
- experimental study planned
- Study period:
- Subject to approval by ECHA
Data source
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 414 (Prenatal Developmental Toxicity Study)
Test material
- Reference substance name:
- Tank fume condensate derived from Residues (petroleum), thermal cracked vacuum (CAS No 92062-05-0)
- IUPAC Name:
- Tank fume condensate derived from Residues (petroleum), thermal cracked vacuum (CAS No 92062-05-0)
- Details on test material:
- Based on historical data, the proposed test material (worst case approach) is a liquid condensate collected from the headspace of a heated tank of Residues (petroleum), thermal cracked vacuum (CAS No 92062-05-0): A complex combination of hydrocarbons obtained from the vacuum distillation of the products from a thermal cracking process. It consists predominantly of hydrocarbons having carbon numbers predominantly greater than C34 and boiling above approximately 495°C (923°F). More information on the worst case approach in sample selection is provided in the testing proposal.
Remark: Study proposal to meet REACH Annex X (8.7.2) requirements.
Constituent 1
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- inhalation
- Details on study design:
- Species: Rat. Female
Route: Inhalation (aerosol/vapour mix from tank fume condensate)
Doses: 3 levels, controlling for respiratory tract irritation
Species: Rat. Female
Route: Inhalation (aerosol/vapour mix from tank fume condensate)
Doses: 3 levels, controlling for respiratory tract irritation
Test Material: Based on historical data, the proposed test material (worst case approach) is a liquid condensate collected from the headspace of a heated tank of Residues (petroleum), thermal cracked vacuum (CAS No 92062-05-0): A complex combination of hydrocarbons obtained from the vacuum distillation of the products from a thermal cracking process. It consists predominantly of hydrocarbons having carbon numbers predominantly greater than C34 and boiling above approximately 495°C (923°F). More information on the worst case approach in sample selection is provided in the testing proposal.
Remark: Study proposal to meet REACH Annex X (8.7.2) requirements.
Results and discussion
Results (fetuses)
Fetal abnormalities
- Abnormalities:
- not specified
Overall developmental toxicity
- Developmental effects observed:
- not specified
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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