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Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The 96h LC50 of 2.14 mg/L (active ingredient) was determined in an acute toxicity test with Danio rerio according to OECD TG 203 under GLP conditions (Reliability 1).

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
2.14 mg/L

Additional information

The acute toxicity to fish was performed in a study according to OECD TG 203 under GLP. The test was assigned reliability 1 as all validity criteria were fulfilled including complete identification of the test substance and chemical analysis of the test concentrations. The key study is based on 3 -(Isodecyloxy)propylamine acetate (CAS no 28701 -67 -9). The results of this study have been read-across to 3 -(Isodecyloxy)propylamine. The two substances have the same chemical structure. The only difference -the presence of acetate in the test substance- is not expected to have an impact on the toxicity.

The key study was performed with Danio rerio under semi-static conditions using natural river water. The nominal test concentrations were 1.00 – 2.20 – 4.84 – 10.6 – and 23.4 mg/L. The measured concentrations of 3-(Isodecyloxy)propylamine acetate in freshly prepared media were in the range of 96 – 102 % and in 24 h aged test media in the range of 65 - 91 % of the nominal values, respectively. Results showed that about 1% of the 2.2 mg/L, sorbed to glassware in the test.


The LC50 (96 h) was calculated to be 2.20 mg/L based on the nominal concentration of the test material (96.2% active ingredient). The LC50 converted to active ingredient is 2.14 mg/L.