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Toxicological information

Carcinogenicity

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Administrative data

Description of key information

Although no specific data could be identified for nonanol branched and linear, weight of evidence across the category suggests that the substance is unlikely to be carcinogenic.

Key value for chemical safety assessment

Justification for classification or non-classification

Based on the weight of evidence, the data is waived as testing is not a scientifically necessary option for this endpoint.

Additional information

Although Column 2 of REACH Annex X requires a carcinogenicity study (required in Section 8.9.1) if the substance has a wide dispersive use, the weight of evidence across the category suggests that nonanol, branched and linear is unlikely to be carcinogenic. This is based on a large set of various types of repeated dose studies across the category which do not offer any evidence of treatment-related induction of hyperplasia / pre-neoplastic lesions for structurally related alcohols (though reporting is limited in many cases). In addition,nonanol does not have any genotoxic effects.