Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (corrosive)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irreversible damage)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Skin irritation/corrosion

The SDS from Acros refers to corrosive (C;R34) based on an OECD TG404 study with necrosis after 60 minutes

2,2,6,6 -tetramethylpiperidin-4 -ol (the analogue substance with no methyl group on N) is highly irritating in an OECD TG404 study

The OECD toolbox study finds this substance irritating

Conclusion: the substance is C;R34 (conservative approach), which translates under GHS to Corrosive Category 1 with pictogram GHS05 (corrosion), signalword Danger and H314: Causes severe skin burns and eye damage

Eye irritaion/corrosion

Only the OECD toolbox v3.4 study is available. This finds the substance irritating


Effects on skin irritation/corrosion: corrosive

Effects on eye irritation: highly corrosive

Justification for classification or non-classification

The substance must be classified as corrosive to skin and eye Category 1 with pictogram GHS05 (corrosion), signalword Danger and H314: Causes severe skin burns and eye damage