Registration Dossier
Registration Dossier
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EC number: 219-292-8 | CAS number: 2403-89-6
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irreversible damage)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Skin irritation/corrosion
The SDS from Acros refers to corrosive (C;R34) based on an OECD TG404 study with necrosis after 60 minutes
2,2,6,6 -tetramethylpiperidin-4 -ol (the analogue substance with no methyl group on N) is highly irritating in an OECD TG404 study
The OECD toolbox study finds this substance irritating
Conclusion: the substance is C;R34 (conservative approach), which translates under GHS to Corrosive Category 1 with pictogram GHS05 (corrosion), signalword Danger and H314: Causes severe skin burns and eye damage
Eye irritaion/corrosion
Only the OECD toolbox v3.4 study is available. This finds the substance irritating
Effects on skin irritation/corrosion: corrosive
Effects on eye irritation: highly corrosive
Justification for classification or non-classification
The substance must be classified as corrosive to skin and eye Category 1 with pictogram GHS05 (corrosion), signalword Danger and H314: Causes severe skin burns and eye damage
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